姓名：陈文川

职称：教授

所在学系：华西口腔医学院

研究生导师类别：硕导/博导

联系方式：（邮箱）hxkqcwc@scu.edu.cn

研究领域：口腔种植修复、组织再生

个人简介

陈文川教授，博士研究生导师。现任四川大学华西口腔医院锦江门诊部主任，二级专家。先后任修复学系、修复I科及固定修复教研室副主任。口腔种植学硕士、固定修复学博士、世界第一所牙学院——美国马里兰大学牙学院博士后。兼任国家口腔医学中心口腔全科专科联盟副主任，四川省卫生健康委学术技术带头人后备人选，中华口腔医学会口腔修复学专业委员会委员，中华口腔医学会口腔美学专业委员会委员，四川省口腔医学会社区口腔医疗专业委员会副主任委员，四川省口腔医学会口腔修复学专业委员会常委，四川省口腔医学会口腔美学专业委员会常委，四川省医学会医学美学与美容专业委员会委员。 先后主持国家自然科学基金4项及省部级等其他课题10余项。Chinese Chemical Letters青年编委，在国内外著名期刊发表专业学术论文70余篇。荣获华夏医学科技奖三等奖，四川大学创新创业优秀指导教师等奖项，获授权种植相关专利8项。主译《美学修复：材料选择与技术（第3版）》。 长期从事口腔种植与修复的医教研工作，具有丰富的临床工作经验。擅长以微创、精密、美观的技术方法进行各种固定修复、种植修复及联合修复。

代表性论文/著作

1.Zheng Z, Ao XG, Xie P, Jiang F, Chen WC*. Proposal and In-depth Analysis of Emergency Treatment Procedures for Removing Fractured Abutments in Implants with Tapped-in Connections: Case Report. J Oral Implantol.2020. 46(1): 51-56.

2.Zheng Zheng, Xiaogang Ao, Peng Xie, Jie Wu, Yuqing Dong, Deping Yu, Jian Wang, Zhimin Zhu, Hockin H. K. Xu, Chen WC*. Effects of novel non‐thermal atmospheric plasma treatment of titanium on physical and biological improvements and in vivo osseointegration in rats. Sci Rep. 2020, 10(1):10637.

3.敖小刚，陈文川*. 低温等离子体促进钛种植体骨结合的研究进展. 华西口腔医学杂志.  2020. 38(5):566-570.

4.Zheng Zheng, Xiaogang Ao, Peng Xie, Fan Jiang, Chen WC*. The biological width around implant. J Prosthodont Res. 2021, 65:11-18.

5.陈姝江, 陈文川*. 牙种植位点复合组织缺损增量时机与方式的选择. 口腔医学研究. 2021. 37(05): 393-396.

6.陈静，陈文川*. 瓷表面处理用氢氟酸替代物四丁基双氟氢氟化铵研究进展. 口腔疾病防治. 2021, 29(9): 629 633.

7.Su C, Zheng X, He YJ, Long L, Chen WC*. Transcriptomic profiling and functional prediction reveal aberrant expression of circular RNAs during osteogenic differentiation in human umbilical cord mesenchymal stromal cells. Sci Rep. 2021. 11(1): 19881.

8.Zheng Z, Ao XG, Xie P, Zheng X, Lee K, Chen WC*. Nonthermal Plasma Brush Treatment on Titanium and Zirconia To Improve Periabutment Epithelium Formation. ACS Biomater Sci Eng. 2021. 7(11): 5039-5047. 

9.何彦瑾, 陈文川*. 智能生物材料在口腔领域中的应用. 口腔医学研究. 2022. 38(01): 9-12.

10.Zheng X, Gan SQ, Su C, Zheng Z, Liao Y, Shao JJ, Zhu ZM, Chen WC*. Screening and preliminary identification of long non-coding RNAs critical for osteogenic differentiation of human umbilical cord mesenchymal stem cells. Bioengineered. 2022. 13(3): 6880-6894.

11.张敏, 敖小刚, 郑铮, 陈文川*. 低温等离子体促进人牙龈上皮细胞在钛表面的黏附. 华西口腔医学杂志. 2022. 40(03): 285-292.

12.Zheng Z, He YJ, Long L, Gan SQ, Chen SJ, Zhang M, Xu J, Fu RJ, Liao YH, Zhu ZM, Wang H*, Chen WC*. Involvement of PI3K/Akt signaling pathway in promoting osteogenesis on titanium implant surfaces modified with novel non-thermal atmospheric plasma. Front Bioeng Biotechnol. 2022. 10: 975840.

13.Long L, Zhang M, Gan S, Zheng Z, He Y, Xu J, Fu R, Guo Q, Yu D, Chen WC*. Comparison of early osseointegration of non-thermal atmospheric plasma-functionalized/SLActive titanium implant surfaces in beagle dogs. Front Bioeng Biotechnol. 2022. 10: 965248.

14.Zhang M, Zhang X, He YJ, Gan SQ, Xie X, Zheng Z, Liao JF*, Chen WC*. Engineered cells-overexpression of circular RNA hybrid hydrogels promote healing of calvarial defects. Biomater Sci. 2023,11(5): 1665-1676.

15.Gan SQ, Wu Y, Zhang X, Zheng Z, Zhang M, Long L, Liao JF*, Chen WC*. Recent Advances in Hydrogel-Based Phototherapy for Tumor Treatment. Gels. 2023,9(4): 286.

16.Chen SJ, Lu M, Zhu ZM, Chen WC*. Clinical performance of two onlay designs for molars after root canal treatment. J Oral Sci. 2023,65(3):171-175.

17.Gan SQ, Zheng Z, Zhang M, Long L, Zhang X, Tan B, Zhu ZM, Liao JF*, Chen WC*. Lyophilized Platelet-Rich Fibrin Exudate-Loaded Carboxymethyl Chitosan/GelMA Hydrogel for Efficient Bone Defect Repair. ACS Appl Mater Interfaces. 2023,15(22): 26349-26362.

18.Xu J, Chen CF, Gan SQ, Liao YH, Fu RJ, Hou CP, Yang SH, Zheng Z, Chen WC*. The Potential Value of Probiotics after Dental Implant Placement. Microorganism. 2023,11(7): 1845.

19.Chen SJ, Duan XQ, He YJ, Chen WC*. METTL3 promotes osteogenic differentiation of human umbilical cord mesenchymal stem cells by up-regulating m6A modification of circCTTN. Bioscience Reports. 2024,44(3): BSR20231186.

20.Liao YH, Xu J, Zheng Z, Fu RJ, Zhang XY, Gan SQ, Yang SH, Hou CP, Xu HHK, Chen WC*. Novel Nonthermal Atmospheric Plasma Irradiation of Titanium Implants Promotes Osteogenic Effect in Osteoporotic Conditions. ACS Biomater Sci Eng. 2024. 10(5): 3255-3267. 

21.Zheng JY, Wang F, Zhang Y, Zheng Z, Wu JH, Ren X, Su Z, Chen WC*, Wang TL*. Novel Stereo-Induction Pattern in Pudovik Addition/Phospha-Brook Rearrangement towards Chiral Trisubstituted Allenes. Angew Chem Int Ed Engl, 2024,63(22): e202403707.

22.Wei X, Lei L, Luo L, Zhou Y, Zheng Z*, Chen WC*. Advances in osteoimmunomodulation of biomaterials after intrabone implantation: focus on surface hydrophilicity. J Mater Chem B. 2024. 12(43): 11089-11104. 

23.Zheng Z, Gan SQ, Yang SH, Hou CP, Zhu ZM, Wang H, Yu DP, Qian ZY, Xu HK, Chen WC*. Enhanced surface hydrophilicity improves osseointegration of titanium implants via integrin-mediated osteoimmunomodulation. J Mater Chem B. 2025. 13(2): 496-510.

24.Yang SH, Zheng Z, Zhang M, Tan BW, Zhang XY, Chen WC*, Liao JF*. Self-degradable nanoparticles hybrid hydrogel with cascade thermal control and spontaneous ion release for complex bone defect regeneration. Chemical Engineering Journal. 512(2025)162653.

25.陆萌, 陈文川*, 高一. 龈下牙体缺损修复中预防牙周疾病的策略. 国际口腔医学杂志. 2025. 52(2): 238-245. 26.蔡嘉宁，余德平*，巩晓菲，薛嘉清，张佳诚，郑铮，陈文川*. 用于氧化锆模拟种植体表面亲水改性的新型等离子体处理系统. 真空. 2025. 62(3):58-64.

其他