硕导
罗小波
姓名:罗小波
职称:副教授
所在学系:口腔内科学系
研究生导师类别:硕导
联系方式:xiaobol@scu.edu.cn
研究领域:口腔黏膜癌变
个人简介
长期以口腔黏膜癌变的免疫机制及其靶向价值为研究方向展开相关研究,围绕这一研究方向,共获得多项科研项目的资助,包括国家自然科学基金青年基金和面上项目各1项、中国博士后科学基金1项、四川省重点研发项目1项等7个项目,并以第一作者或通讯作者身份在国际知名期刊上发表论文16篇,其中包括国际权威的The Journal of Clinical Investigation和口腔医学权威期刊Journal of Dental Research,材料学领域权威期刊ACS applied materials & interfaces(封面文章),免疫学领域知名期刊Frontiers in immunology等;其中,一作发表于The Journal of Clinical Investigation的论文首次揭示了HPV病毒介导头颈部鳞状细胞癌免疫逃逸的关键分子机制;通讯作者发表于ACS AMI的论文表明,基于原儿茶酸的超分子水凝胶可通过靶向Sb9,增强T细胞来源GrzB的抗肿瘤作用;现论文总计他引160余次。作为执笔人之一负责1项中华口腔医学会行业指南并已发布,参与2项中华口腔医学会行业指南编写。主讲的本科课程曾获“四川大学课堂教学质量优秀奖”及“第二批四川省级一流本科课程”。现任中华口腔医学会第八届口腔黏膜病学专业委员会青年委员,四川省口腔医学会第三届口腔黏膜病(中西医)专委会青年委员组长,四川省中西医结合学会眼与全身病专委会委员。
代表性论著
1. Xiaobo Luo, Christopher R. Donnelly, Wang Gong, Blake R. Heath, Yuning Hao, Lorenza A. Donnelly, Toktam Moghbeli, Yee Sun Tan, Xin Lin, Emily Bellile, Benjamin A. Kansy, Thomas E. Carey, J. Chad Brenner, Lei Cheng, Peter J. Polverini, Meredith A. Morgan, Haitao Wen, Mark E. Prince, Robert L. Ferris, Yuying Xie, Simon Young, Gregory T. Wolf, Qianming Chen*, and Yu L. Lei*. HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING. The Journal of Clinical Investigation. 2020;130(4):1635-1652.
2. Xiaobo Luo, Yuchen Jiang, Fangman Chen, Zihao Wei, Yan Qiu, Hao Xu, Guoli Tian, Wang Gong, Yao Yuan, Hui Feng, Liang Zhong, Ning Ji, Xiaoping Xu, Chongkui Sun, Taiwen Li, Jing Li, Xiaodong Feng, Peng Deng, Xin Zeng, Min Zhou, Yu Zhou, Hongxia Dan, Lu Jiang *, Qianming Chen*. ORAOV1-B promotes OSCC metastasis via the NF-κB-TNFα loop. Journal of Dental Research. 2021;100(8):858-867.
3. Xiaobo Luo#, Yan Qiu#, Yuchen Jiang, Fangman Chen, Lu Jiang, Yu Zhou, Hongxia Dan, Xin Zeng, Yu L. Lei*, Qianming Chen*. Long non-coding RNA implicated in the invasion and metastasis of head and neck cancer: possible function and mechanisms. Molecular Cancer. 2018; 17(1):14.
4. Zaiye Li#, Lideng Cao#, Chengcan Yang, Tiannan Liu, Hang Zhao, Xiaobo Luo*, Qianming Chen*. Protocatechuic acid based-supramolecular hydrogel targets Sb9 to achieve local chemotherapy for OSCC, ACS Applied Materials&interfaces. 2022; 14(32): 36379−36394.(封面文章)
5. Chunyu Li, Yuqi Wu, Yulang Xie, You Zhang, Sixin Jiang, Jiongke Wang, Xiaobo Luo*, Qianming Chen*. Oral manifestations serve as potential signs of ulcerative colitis: A review. Frontiers in immunology. 2022; 13:1013900.